All Externally Funded Projects at FMR

  1. IMMLEP/WHO – 1978-1979 (2 years) – In vitro interaction between macrophages, lymphocytes and M.leprae - $ 6,000.
  2. THELEP/WHO - 1978-1979 (2 years) - Study of bacterial load and viability of M.leprae in human nerves - $ 5,700.
  3. Indian Council of Medical Research - 1982-1984 (2 years) - Macrophage mediated in vitro tests for screening immunomodulating mycobacterial strains - Rs.125,000.
  4. PL-480 - 1982-1985 (3 years) - Use of biochemical and radioisotope methods for developing improved techniques for in vitro detection of drug resistance and screening of new drugs for leprosy - Rs.720,355.
  5. Indian Council of Medical Research - 1982-1985 (3 years) - Studies on metabolism of M.leprae - Rs.204,471.
  6. IMMLEP/WHO - 1984-1985 (2 years) - Role of macrophages in defective immunity in leprosy - $ 32,000.
  7. Indo-US - 1984-1985 (2 years) - Characterization of the specific phenolic glycolipid from human derived M.leprae - Rs.130,170.
  8. Indo-US - 1984-1986 (2 years) - Determining the antigenic and biochemical phenotypes of mononuclear phagocytes in blood and tissues of leprosy patients - Rs.125,000.
  9. The Wellcome Trust - 1985-1987 (2 years) - Role of cell mediated immunity in nerve damage in leprosy:  An in vitro study with special reference to the Schwann cell - $ 25,000.
  10. German Leprosy Relief Association - 1985-1987 (3 years) - Determination of anti-M.leprae activity of new test compounds by rapid in vitro assays - $ 34,800.
  11. THELEP/WHO - 1986-1987 (6 months) - Initial grant for: An in vitro method of screening for sensitivity and resistance to anti-leprosy drugs using the Schwann cell model - $ 5,000.
  12. German Leprosy Relief Association - 1986 (1 year) - An immunodiagnostic test system for follow-up of patients under multidrug therapy - $ 12,000.
  13. Indian Council of Medical Research - 1986-1988 (2 years) - A field trial of the value of macrophage EA rosetting as an in vitro method for screening of drug resistance/sensitivity in lepromatous leprosy - Rs.81,800.
  14. Department of Science and Technology - 1986-1989 (3 years) - Molecular biology of leprosy infection and development of immune modulators for immuno-therapy as well as possible application of recombinant DNA techniques for large scale production of such immuno-modulators  - Rs.487,000.
  15. NESTEC - 1987-1989 (2 years) - DFS creatinine sulphate, preclinical in vitro and in vivo assessment of its efficacy as an anti-leprosy drug - Rs.134,000.
  16. Department of Science and Technology - 1988-1990 (3 years) - Mechanisms of peripheral nerve damage in leprosy and approaches for its prevention and treatment - Rs.1,465,105.
  17. German Leprosy Relief Association - 1988-1990 (2 years) - An immunodiagnostic test system for follow-up of patients under multidrug therapy - $ 35,000.
  18. The Wellcome Trust - 1989-1991 (2 years) - Effect of macrophages and extracellular matrix proteins on Schwann cell response to M.leprae infection - £ 54,000.
  19. LEPRA - 1989-1991 (2 years) - Functional and morphological study of peripheral nerves in leprosy following MDT in paucibacillary and multibacillary cases - £ 22,000.
  20. Department of Biotechnology - 1989-1991 (3 years) - Development and field adaptation of a subunit/recombinant DNA protein as a vaccine for leprosy – Rs.2,500,000.
  21. Indian Council of Medical Research - 1989-1990 (2 years) - Role of ROI in killing of M.leprae in cells of leprosy patients and the possibility of modulation of ROI in deficient cells of the host  - Rs.87,000.
  22. Sir Dorabji Tata Fellowship - 1990 (1 year) - Mycobacterial antigen presentation by macrophages - Rs.5,000.
  23. Indian Council of Medical Research - 1990 (1 year) - Strategy for a possible new vaccine against leprosy: use of a gene product - Rs.100,000.
  24. NORAD (Under the Indo-Norwegian Institute Collaboration Scheme) - 1991-1994 (3 years) - Isolation, characterization and use of secretory mycobacterial antigens for assessment of multidrug therapy in leprosy and tuberculosis - Rs.2,700,000.
  25. NESTEC - 1991-1992 (2 years) - Deoxyfructo serotonin (DFS) creatinine sulphate - Preclinical in vitro and in vivo assessment of its efficacy as an anti-leprosy drug – Rs.340,000.
  26. German Leprosy Relief Association - 1991-1992 (2 years) - To develop a cascade test system for locating "susceptible" individuals for paucibacillary and multibacillary type of leprosy in close contacts of leprosy patients - Rs.629,000.
  27. Gulbarga University - 1991-1992 (15 months) - In vivo and in vitro screening of compounds from Gulbarga University for anti-M.leprae potential  - Rs.50,000.
  28. Sir Dorabji Tata Trust - 1993 (6 months) - An enquiry into the utilization of ayurvedic health care with special reference to diarrhoeal patients - Rs.30,000.
  29. Lupin Laboratories Limited - 1993-1994 (17 months) - Evaluation of anti-leprosy action of "compound IB" in the mouse leprosy model - Rs.591,164.
  30. Sir Dorabji Tata Trust and Sir Ratan Tata Trust - 1994-1995 (2 years) - Evaluation of ayurvedic treatment for the control of diarrhoeal diseases - Rs.330,000.
  31. The Industrial Credit and Investment Corporation of India Limited - 1995 -1996 (1 year) - Infrastructure for diagnosis and testing of multidrug resistance in tuberculosis - Rs.750,000.
  32. Lady Tata Memorial Trust - 1995-1997 (2½ years) - Studies on structural and biochemical aspects of axonal atrophy in leprosy - Rs.78,000.
  33. The John D and Catherine T. MacArthur Foundation - 1995-2000 (5 years) - Reproductive tract problems in rural and urban women and their implications in HIV infection - $264,782.
  34. Department of Science and Technology - 1996-1999 (3 years) - Structural and biochemical basis of axonal atrophy in leprosy - Rs.1,280,050.
  35. The Industrial Credit and Investment Corporation of India Limited - 1996-1998 (2 years) - Optimizing treatment of HIV related tuberculosis - Rs.800,000.
  36. Bombay Community Public Trust - 1996-1998 (2 years) - Provision of comprehensive laboratory services for TB control in Bombay - Rs.600,000.
  37. Project Concern International - 1998 (1 year) - Upgrading of equipment and facilities for laboratory testing of drug resistance in leprosy patients - $ 23,702.
  38. Leprosy Mission India and J.R.D. Tata Educational Trust - 1998-2000 (2 years) – Significance of recurrence of skin and nerve lesions after MDT in MB leprosy – Rs.1,200,000.
  39. DFID India - 1999 (3 months) - Maharashtra rural water supply and sanitation project: Health impact assessment study - Rs.1,156,050.
  40. The Wellcome Trust - 2000-2001 (6 months) - Training and technology transfer in molecular techniques to study M.tuberculosis strain variations - £ 7,220.
  41. American Leprosy Mission - 2001-2006 (5 years) - Effect of corticosteroid usage on the bacterial killing, clearance and nerve damage in leprosy: A prospective cohort study - $105,000.
  42. Department of Science and Technology - 2002-2004 (2 years) - The documentation, study, propagation and utilization of local medicinal plants with antidiarrhoeal activity in the Parinche Valley (Maharashtra) - Rs.1,410,000.
  43. Indian Council of Medical Research – 2003-2005 (2 years) – To study the potential of Buddemeyer type radiorespirometric assay based on CO2 evolution from (1-14C) palmitic acid by M.leprae as a rapid index of viability – Rs.786,400.
  44. Department of Science and Technology - 2003-2006 (3 years) - Deciphering the role of M.leprae antigens and host derived factors in the induction of cytoskeletal protein abnormality and neural dysfunction using an experimental model depicting silent nerve damage in leprosy - Rs.1,500,000.
  45. Tata Education Trust – 2003-2007 (4 years) – Study of the effect of BCG immunotherapy as an adjunct to chemotherapy on the M.leprae persisters and peripheral nerve functions – Rs.3,750,000.
  46. Narotam Sekhsaria Foundation – 2003-2004 (18 months) – An integrated biosocial approach for control of water-borne diseases in a rural community in Western Maharashtra – Rs.900,000.
  47. The Industrial Credit and Investment Corporation of India Limited – (One Time Grant) – Instrumentation grant for MDR-TB project – Rs.350,000.
  48. The Wellcome Trust (UK) – 2004 -2007 (4 years) – Construction of an epidemiological framework for MDR- TB in urban and rural areas of Western India -  £161,078
  49. Sardar Patel University, Vallabh Vidyanagar – 2005-2007 (2 years) – Testing of anti-malarial activity of herbal preparation in the mouse model – Rs.250,000.
  50. Indian Council of Medical Research – 2006-2010 (4 years) – Underlying mechanism/s and precipitating factor/s involved in reversal reactions (RR) and nerve damage in leprosy. – Rs.2,993,654.
  51. Department of Biotechnology 2007—2012 (5 years) – Recognized as Virtual Centre of Excellence for Tuberculosis Research : Mechanisms of introduction, selection, maintenance and modulation of drug resistance in Mycobacterium tuberculosis through a functional genomics approach – Rs.22,221,000.
  52. Indian Council of Medical Research – 2007-2010 (3 years) – Development of a herbal package with antidiarrhoeal activity and its popularisation in a rural community - Rs.2,769,083.
  53. Swiss Emmaus Leprosy Relief Work – India 2007 – 2008 (1½ years) – Detection of previously undetected leprosy cases in a defined rural and urban area of Maharashtra, Western India – Rs.538,611.
  54. Government of Maharashtra  - 2009 – Implementation of Selective Special Drive (SSD) in Gadchiroli, Maharashtra – Rs.765,000.
  55. Royal Tropical Institute, The Netherlands – 2011 – 2013 (3 years) – Treatment of early neuropathy in leprosy (TENLEP) trials - € 99,489.
  56. Jamsetji Tata Trust – 2011 – 2013 (3 years) – Utilization of individual household kitchen gardens and other interventions to improve family nutritional levels in Melghat – Rs.5,491,000.
  57. Indian Council of Medical Research – 2011 – 2014 (3 years) – Occurrence of drug resistance among relapse cases, poor responders and new cases of leprosy – A Multicentric study in India – Rs.6,369,347
  58. Novartis Foundation, Switzerland – 2011 – Childhood leprosy in India – Rs.300,000.
  59. Norway Research Council, Norway – 2012 – 2015 (4 years)   - Too-India-Too much, too less, too bad? – Adapting to climate change impacts on water quantity and quality in the drylands of Maharashtra, India” – NOK 1,443,533
  60. London School of Hygiene and Tropical Medicine, London – 2012 – 2013 (7 months) – Neuropathic pain in leprosy study – Rs.497,000.
  61. Indian Council of Medical Research – 2012 – 2014 (2 years) – Socio-cultural features of leprosy for treatment and control in primary health services in India –  Rs.2,864,000.
  62. Bombay Community Public Trust – 2012 – 2013 (7 months) - Assessment of tuberculosis in correctional and congregate settings in Mumbai – Rs.250,000.
  63. Department of Biotechnology – 2013 – 2015 (2 years) – “NANOCOS” : Chitosan oligosaccharide-siRNA nanoplexes for inhibiting intracellular mycobacteria – Rs.791,600.
  64. Department of Science and Technology – 2013 – 2016 (3 years) – Transcriptional analysis of genes associated with rapid acquisition of multi drug resistance in Mycobacterium tuberculosis – Rs.5,500,000
  65. Bill & Melinda Gates Foundation, USA – 2013 – 2016 (3 years)  - Patient Pathways to tuberculosis care in Mumbai and Patna -  Rs.22,249,764.
  66. Vasant J Sheth Memorial Foundation – 2014 – Kaula Bundar : A Prototype for active tuberculosis case finding in Mumbai – Rs..433,800.

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