projects 2008-2012

ongoing projects

Leprosy

Publications

  1. Khodke AS, Shetty VP.   Type 1 reaction masquerading clinically as ENL: A Case Report. Lepr. Rev, 2015. In Press.
  2. Lockwood D NJ, Shetty VP, Penna OP. Hazards of setting targets to eliminate disease: lessons from the leprosy elimination campaign. BMJ, 2014, 348: g1136.
  3. Shetty VP, Ghate SD, Wakade AV, Thakar DV, D’Souza D. Clinical bacteriological and histopathological characteristics of newly detected children with leprosy: A population based study in a defined rural and urban area of Maharashtra, Western India. Indian J. Dermatol. Venerol. Leprol., 2013, 79: 512-517.
  4. Shetty VP, Mistry NF, Wakade AV, Ghate SD,  Capadia GD, Pai VV. BCG immunotherapy as an adjunct  to chemotherapy in BL-LL patients-its effects on clinical regression, reaction, severity, nerve function, lepromin conversion, bacterial /antigen clearance and ‘persister’ M. leprae . Lepr. Rev., 2013, 84: 23-40.
  5. Shetty VP, Pandaya SS. One year follow up of a cohort of suspected leprosy cases: Finding from a leprosy ‘Selective Special Drive’ in Gadchiroli District, Maharashtra, India. Lepr. Rev., 2012, 83: 64-70.
  6. Kuruwa S, Vissa V, Mistry NF. Distribution of Mycobacterium leprae strains among cases in rural and urban population of Maharashtra, India. J. Clin. Microbiol., 2012, 50: 1406-1411.
  7. Atre SR, Rangan S, Shetty VP, Giakwad N, Mistry NF.
    Perceptions health seeking behavior and access to diagnosis and treatment initiation among previously undetected leprosy cases in rural Maharashtra, India. Lepr. Rev., 2011, 82: 222-234.
  8. Shetty VP, Wakade AV, Ghate SD, Pai VV. Clinical, bacteriological and histopathological study of 62 referral relapse cases between Jan. 2004 and Dec. 2009 at Foundation for Medical Research, Mumbai. Lepr. Rev., 2011, 82: 235-243.
  9. Boga P, Shetty VP, Khan Y. Nitric oxide metabolites in sera of patients across the spectrum of leprosy. Indian J. Lepr., 2010, 82: 123-129.
  10. Shetty VP, Khambati FA, Ghate SD, Capadia GD, Pai VV,  Ganapati R. The effect of corticosteroids usage on the bacterial killing, clearance & nerve damage in Leprosy; Part 3- Study of two Comparable groups of 100 multibacillary (MB) patients each, treated  with MDT+ steroids versus MDT alone, assessed at 6 months post release from 12 months MB-MDT. Lepr. Rev., 2010, 81: 41-58.
  11. Capadia GD, Shetty VP, Khambati FA, Ghate SD.  Effect of corticosteroid usage along with multi-drug therapy on nerve damage assessed using nerve conduction studies: A prospective cohort study of 365 untreated multibacillary (MB) leprosy patients.  J. Clin. Neurophysiol., 2010, 27: 38-47.
  12. Shetty VP. Challenges facing the control of leprosy in Indian context. Ann. Acad. Med. Singapore, 2010: 21-27.
  13. Gupta UD, Shetty VP.  Drug resistance studies, viability and bacterial persisters and animal models in leprosy: In IAL Text book of Leprosy Kar Hemant Kumar and Bhushan Kumar, (ed.) Ch38, Jaypee Brothers Medical Publishers (P) Ltd., 2010: Pg 492-502.
  14. Shetty VP. Patho-mechanisms of Nerve Damage: In IAL Textbook of Leprosy Kar Hemant Kumar and Bhushan Kumar, (ed.) Ch19 Jaypee Brothers Medical Publishers (P) Ltd., 2010: pg 237-247.
  15. Shetty VP, Pandya SS, Arora S, Capadia GD. Observations from a ‘Special selective drive’ conducted under National Leprosy Elimination. Programme in Karjat taluka and Gadchiroli district of Maharashtra. Indian J. Lepr., 2009, 81: 189-193.
  16. Save MP, Shetty VP, Shetty KT.  Hypophosphorylation of NF-H and NF-M subunits of neurofilaments and the associated decrease in KSPXK kinase activity in the sciatic nerves of Swiss White mice inoculated in the foot pad with Mycobacterium leprae. Lepr. Rev., 2009, 80: 388-407.
  17. Khambati FA, Shetty VP, Ghate SD, Capadia GD. Sensitivity and specificity of nerve palpation, monofilament testing and voluntary muscle testing in detecting in peripheral nerve abnormality, using nerve conduction velocity as gold standard: A study in 400 untreated multibacillary leprosy patients. Lepr. Rev., 2009, 80: 34-50.
  18. Shetty VP, Thakar UH, D’Souza E, Ghate SD, Arora S, Doshi P, Wakade AV, Thakur DV. Detection of previously undetected Leprosy cases in a defined Rural and Urban area of Maharashtra, Western India. Lepr. Rev., 2009, 80: 22-33.
  19. Shetty VP, Doshi RP. Detection and classification of Leprosy: future needs and Strategies. Indian J. Lepr., 2008, 80:139-147.
  20. Khambati FA, Shetty VP, Ghate SD, Pai VV, Ganapati R. Effect of corticosteroid usage on the bacterial killing, clearance and nerve damage in leprosy: A prospective cohort study: Part 1. Study design and baseline findings in 400 MB cases presenting with and with out reaction.  Lepr. Rev., 2008, 79: 134-153.
  21. Shetty VP, Van Brakel WH, Saunderson P, Brandsma JW, Post E, Jellema, Remke, Mcknight, Jason. International workshop on neuropathology in leprosy – consensus report.  Lepr. Rev., 2007, 78: 416-433.
  22. Wakade AV, Shetty VP. Effect of cryo preservation on Mycobacterium leprae growth in the foot pads of non immunosuppressed mice.  Lepr. Rev., 2007, 78: 381-385.
  23. Agrawal VP, Shetty VP. Comparison of the mouse foot pad test with a Buddemeyer type radiorespirometirc assay in detecting viable Mycobacterium leprae in human lesional biopsies. Indian J. Dermatol. Venerol. Leprol., 2007, 73: 384-388.
  24. Agrawal VP, Shetty VP. Comparison of radiorespirometric Buddemeyer assay with ATP assay and mouse foot pad test in detecting viable Mycobacterium leprae from clinical samples. Indian J. Med. Microbiol., 2007, 25: 358-363.
  25. Shetty VP, Wakade AV. Isolation of Mycobacterium leprae from untreated borderline tuberculoid, mid-borderline and indeterminate cases using the mouse food pad technique- A study of 209 cases. Lepr. Rev., 2006, 77: 336-370.
  26. Pandya SS, Shetty VP. The Neuropathy of Leprosy. An Indian Perspective. Elsevier, 2005.
  27. Shetty VP, Wakade AV, Ghate SD, Pai VV, Ganpati RR, Antia, NH. Clinical and histopathological and bacteriological study of 52 referral MB cases relapsing after MDT. Lepr. Rev., 2005, 76: 241-252.
  28. Save MP, Shetty VP, Shetty KT, Antia NH. Part 1: Alterations in neurofilament protein(s) in human leprous nerves: morphology, immunohistochemistry and Western immunoblot correlative study. Neuropathol. Appl. Neurobiol., 2004, 30: 635-650.
  29. Birdi TJ, Antia NH. Mechanisms involved in peripheral nerve damage in leprosy with special reference to insights obtained from in vitro studies and the experimental mouse model. Int. J. Lepr., 2003, 71: 345-353.
  30. Shetty VP, Wakade AV, Ghate S, Pai VV, Ganapati R, Antia, NH. Viability and drug susceptibility testing of M. leprae using mouse foot pad in 37 relapse cases of leprosy. Int. J. Lepr., 2003, 71: 210-217.
  31. Shetty, VP, Antia NH. Light and ultrastructural study of sciatic nerve lesions induced using intraneural injection of viable Mycobacterium leprae in normal and immunosuppressed Swiss white mice. Int. J. Lepr., 2002, 70: 25-36.
  32. Shetty VP, Mistry NF. Key issues related to bacterial persisters (2002), p. 177–186 In Sood OP and Rattan A (ed.) Leprosy Elimination: Critical issues.  Ranbaxy Science Foundation Round Table Conference Series.
  33. Shetty VP. Advances in methods of isolation, cultivation and testing of drug susceptibility for Mycobacterium leprae. Dr. Ananthnarayan Memorial Microbiology Symposium on Leprosy - APCON 2001 held at Mumbai on 16 December 2001, 21-32.
  34. Shetty VP, Wakade AV, Antia NH. A high incidence of viable Mycobacterium leprae in post MDT recurrent lesions in tuberculoid leprosy patients. Lepr. Rev., 2001, 72: 337-344.
  35. Save MP, Shetty VP. A critique on commentary "How Mycobacterium leprae infects peripheral nerves" by Freedman et al (Letter to the editor). Lepr. Rev., 2001, 72: 102-105.
  36. Shetty VP, Wakade AV, Antia NH, Pai VV, Revankar CR, Ganapati R, Bulchand HO. Clinical, histopathological and bacteriological investigation in two cases of relapse following ROM treatment. Lepr. Rev., 2001, 72: 83-87.
  37. Shetty VP, Mistry NF, Antia NH. Current understanding of leprosy as a peripheral nerve disorder: Significance of involvement of peripheral nerve in leprosy. Indian J. Lepr., 2000, 72: 339-350.
  38. Sethna KB, Iyer AM. Comparative leprosy vaccine trial in South India (Letter to the Editor). Indian J. Lepr., 1999, 71: 477-78.
  39. Shetty VP, Papinder MS, Antia NH. Sciatic nerves of normal and 200 x 5R S/W mice fails to support the multiplication of intranuerally infected M. leprae. Int. J. Lepr., 1999, 67: 446-452.
  40. Shetty VP, Shetty KT, Save MP, Antia NH. M .leprae induced alteration in the neurofilament phosphorylation leads to demyelination in leprous nerves: A hypothesis. Indian J. Lepr., 1999, 71: 121-135.
  41. Mistry NF, Antia NH. Incomplete killing of intracellular mycobacteria - Speculations on the creation of persisters. Indian J. Lepr., 1999, 71: 69-74.
  42. Samant G, Shetty VP, Uplekar MW, Antia NH. Clinical and electrophysiological evaluation of nerve function impairment following cessation of multi drug therapy in leprosy. Lepr. Rev., 1999, 70: 10-20.
  43. Singh N, Birdi TJ, Chandrashekar S, Antia NH. In vitro studies on extracellular matrix production by M. leprae infected murine neurofibroblasts.  Lepr. Rev., 1998, 69: 246-256.
  44. Singh N, Birdi TJ, Antia NH. Collagen profile in sciatic nerves of M. leprae inoculated mice correlates with In vitro collagen production by Schwann cells. Int. J. Lepr., 1998, 66: 238-240.
  45. Singh N, Birdi TJ, Antia NH. Differential In vitro modulation of Schwann cell proliferation by Mycobacterium leprae and macrophages in the murine strains, Swiss white and C57BL/6. J. Peripher. Nerv. Syst. 1998, 3: 207-215.
  46. Sethna KB, Birdi TJ, Antia NH. Adherence of Mycobacterium leprae to the nasal mucosa is influenced by surface integrity and viability. J. Biosci., 1997, 22: 1-9.
  47. Singh N, Birdi TJ, Chandrashekar S, Antia NH. Schwann cell ECM protein production is modulated by M. leprae and macrophage secretory products. J. Neurol. Sci., 1997, 151: 13-22.
  48. Shetty VP, Antia NH. Relapse in a borderline tuberculoid case of leprosy 5 years after the release from rifampicin monotherapy - A case report. Lepr. Rev., 1997, 68: 162-166.
  49. Shetty VP, Suchitra K, Uplekar MW, Antia NH. Higher incidence of viable M. leprae within the nerve as compared to skin among multibacillary leprosy patients released from multidrug therapy. Lepr. Rev., 1997, 68: 131-138.
  50. Antia NH, Shetty VP. (Editors). Peripheral nerve in leprosy and other neuropathies. Oxford University Press, Delhi, 1997.
  51. Singh N, Birdi TJ, Antia NH. Nerve growth factor production and expression of p75 by Schwann cells and neurofibroblasts in response to M.leprae infection and macrophage secretory products. Neuropathol. Appl. Neurobiol., 1997, 23: 59-67.
  52. Birdi TJ, D'Souza S, Antia NH. Expression of mycobacterial antigens on murine dissociated Schwann cells infected with viable M. leprae. Microb. Pathog., 1996, 22: 181-185.
  53. Shetty VP, Mistry NF, Uplekar MW, Antia NH, Pai VV, Ganapati R. Dormancy, drug resistance or dependency-some thoughts to ponder. Int. J. Lepr., 1996, 64: 455-457.
  54. Mistry NF, Iyer A, Harboe M, Antia NH. Low rates of detection of mycobacterial secretory antigen 85 in sera of untreated leprosy patients. Int. J. Lepr., 1996, 64: 451-452.
  55. Shetty VP, Uplekar MW, Antia NH. Primary resistance to single and multiple drugs in leprosy: a mouse foot pad study.  Lepr. Rev., 1996, 67: 280-286.
  56. Birdi TJ, Desai S, Antia NH. Suppression of lymph node lymphoproliferation to viable M. leprae by peripheral blood derived monocytes. Lepr. Rev., 1996, 67: 338-343.
  57. Singh N, Birdi TJ, Antia NH. M. leprae infection and macrophage secretory products modulate the expression of NgCAM on Schwann cell surface. Int. J. Lepr., 1996, 64: 449-451.
  58. Shetty VP, Antia NH. A semi quantitative analysis of bacterial load in different cell types in leprous nerves using transmission electron microscope. Indian J. Lepr., 1996, 68: 105-108.
  59. Shetty VP, Antia NH. Animal model for leprous neuropathy: our contribution. Indian J. Lepr., 1996, 68: 95-104.
  60. Mistry NF, Shetty VP, Antia NH. Nerve tissue culture as an approach towards the study of onset of reaction in the nerve in leprosy - observations and hypothesis. Indian J. Lep., 1996, 68: 67-73.
  61. Antia NH. Leprosy. "Surgical diseases in tropical countries" Eds: Suneet Sood and Anurag Krishna, 1996, 76-83.
  62. Birdi TJ, Shetty VP, Antia NH. Differences in M.leprae-induced nerve damage in Swiss white and C57BL/6 mice. Int. J. Lepr., 1995, 63: 573-574.
  63. Antia NH. Overview of leprosy: Four decades of personal observations. The Star, 1995, 54: 8-9.
  64. Shetty VP, Mistry NF, Birdi TJ, Antia NH. Effect of T-cell depletion on bacterial multiplication and pattern of nerve damage in M. leprae infected mice. Indian J. Lepr., 1995, 67: 363-373.
  65. Save MP, Shetty VP, Antia NH. Intracellular localization of dapsone and rifampicin in skin and nerve of multidrug treated leprosy patients. Indian J. Lepr., 1995, 67: 273-284.
  66. Shetty VP. Polyaxonal myelination in a human leprous nerve. Int. J. Lepr., 1995, 63: 104-105.
  67. Arolkar SK, Antia NH. Vascular surgery of the posterior tibial compartment for plantar ulceration in leprosy. Lepr. Rev., 1995, 66: 48-54.
  68. Leprosy: Report of a Meeting of physicians and scientists (Antia NH, Panel member) at the All India Institute of Medical Sciences, New Delhi. Lancet, 1995, 345: 697-703.
  69. Shetty VP, Uplekar MW, Antia NH. Immunohistochemical localization of mycobacterial antigens within the peripheral nerves of treated leprosy patients and their significance to nerve damage in leprosy. Acta Neuropathol., 1994, 88: 300-306.
  70. Damle A, Mahadevan PR. Nature of peritoneal macrophages from DCC immunized mice. Indian J. Lepr., 1993, 65: 405-414.
  71. Mistry NF, Murthy S, Sethna KB, Kulkarni VC, Harboe MH, Antia NH. Immunodiagnosis of tuberculosis and leprosy. Natl. Med. J. India, 1993, 6: 297.
  72. Mistry NF, Antia NH. Polymerase chain reaction and assessment of leprosy chemotherapy - letter. Lancet, 1993, 342: 1060.
  73. Shetty VP. Animal model to study the mechanism of nerve damage in leprosy: a preliminary report. Int. J. Lepr., 1993, 61: 70-75.
  74. Mahadevan PR. Mycobacteria and the host. Curr. Sci., 1993, 64: 655-659.
  75. Iyer D, Mahadevan PR. Leprosy: Microbiology. Indian J. Microbiol., 1993, 33: 1-23.
  76. Jacobs JM, Shetty VP, Antia, NH. A morphological study of nerve biopsies from cases of multibacillary leprosy given multidrug therapy. Acta Neuropathol., 1993, 85: 533-541.
  77. Joshi S, Nair SC, Mahadevan PR. Antigenic similarity of a cultivable acid fast bacterium to Mycobacterium leprae. Indian J. Med. Res., 1993, 97: 18-24.
  78. Shetty VP, Khade S, Uplekar MW, Antia NH. Persistance of M. leprae in the peripheral nerve as compared to skin of multidrug treated leprosy patients. Lepr. Rev., 1993, 63: 329-336.
  79. Mauron J, Ganapati R, Mahadevan PR, Anantharaman K.  The use of an amino acid as a precursor of a bioactive metabolite in combatting an infectious disease: the efficacy of a tryptophan-enriched diet in the treatment of leprosy. Amino Acids, 1992, 2: 255-269.
  80. Shetty VP, Antia NH. Unusual cells of leprous neuritis: a short communication. Int. J. Lepr., 1992, 60: 483-485.
  81. Mistry NF, Shetty V, Shetty VP, Antia, NH. Ability and functional implications of sensitization of lymphoid cells In vitro by mycobacterial infected Schwann cells. Proceedings of International Conference on Neurobiology: Goa India, 1991. In: Nervous Systems: Principles of design and Function. Edited by R. Naresh Singh 1992, 437-450.
  82. Shetty VP, Mukherjee R, Antia NH. Ultrastructural study of mouse dorsal root ganglion cultures infected long-term with M. leprae. Indian J. Lepr., 1992, 64: 293-301.
  83. Mahadevan PR, Robinson P. Molecular biology of host susceptibility to leprosy in relation to surface properties of macrophages. DAE Symposium on Molecular Biology of Microorganism, National Chemical Laboratory, Pune. 1992, 169-176.
  84. Mahadevan PR, Robinson P, Vermani M, Pardhy A, Joshi S. Delipidified cell components of Mycobacterium Leprae and its applications. Indian J. Lepr., 1991, 63: 371-387.
  85. Antia NH, Mistry NF. Dr. Dharmendra's influence in the various fields of leprosy. Indian J. Lepr., 1991, 63: 297-300.
  86. Mistry Y, Antia NH, Mukherjee R. Radiolabelling of Mycobacterium leprae lipids within Schwannoma cells, a potential drug screening system. Antimicrob. Agents Chemother., 1991, 35: 1444-1447.
  87. Antia NH, Daver BM. Surgery for Leprosy. Natl. Med. J. India, 1991, 4: 236-246.
  88. Antia NH. Surgery for Leprosy. (Editorial). Natl. Med. J. India, 1991, 4: 2-4.
  89. D'Souza S, Mistry NF, Antia NH. Specificity of lymphoid cells within peripheral nerve lesions of paucibacillary leprosy patients. Trop. Med. Parasitol., 1990, 41: 321-323.
  90. Mahadevan PR, Robinson P. An antigenic complex that restores ability in leprosy patients to kill Mycobacterium leprae - The probable molecular events identified by in vitro experiments. Trop. Med. Parasitol., 1990, 41: 310-313.
  91. Nair I, Varadkar D, Mahadevan PR. Viability of Mycobacterium leprae inside macrophages from different strains of mice and possible genetic control. Int. J. Lepr., 1990, 58: 548-553.
  92. Nair I, Mahadevan PR. Antigenic protein from Mycobacterium leprae released In vitro as indicator of viability of bacteria. Int. J. Lepr., 1990, 58: 540-547.
  93. Shetty KT, Naik PM, Mahadevan PR. A specific colorimetric assay for dapsone in biological fluids. Indian J. Clin. Biochem., 1990, 5: 101-109.
  94. Seydel JK, Wempe EG, Rosenfeld M, Jagannathan R, Mahadevan PR, Dhople AM. In vitro and In vivo experiments with the new inhibitor of Mycobacterium leprae brodimoprim aloue and in combination with dapsone. Arznemittelforschung (Drug Research), 1990, 40: 69-75.
  95. Marolia J, Robinson P, Mahadevan PR. A complex component modulating immune-deficient cells in leprosy patients leading to loss of viability of Mycobacterium leprae - a possible vaccine. Clin. Exp. Immunol., 1990, 79: 72-77.
  96. Mahadevan PR. Conceptual basis and practical constraints in screening for viability of Mycobacterium leprae. Indo-UK Workshop on Leprosy Research. Jalma, Agra, 1989, 132-134.
  97. Antia NH, Shetty VP, Mukherjee R. Neural lesions in leprosy. Med. Res., 1989, 1: 61-86.
  98. Choudhury A, Mistry NF, Antia NH. Blocking of Mycobacterium leprae adherence to dissociated Schwann cells by anti-mycobacterial antibodies. Scand. J. Immunol., 1989, 30: 505-509.
  99. Antia NH. Experimental models in leprous neuropathy. (Indo-UK Workshop on Leprosy Research) Lepr. Res. Rev., Jalma, Agra, 1989, 87-91.
  100. Ghaswala PS, Mistry NF, Antia NH. Serum antibodies of normals and leprosy patients show equal binding to peripheral nerve. Int. J. Lepr., 1989, 57: 690-692.
  101. Mester De Parajd M, Ambrose EJ, Tayeb N, Antia NH. Deoxyfructoserotonin: Therapuetic effect in treatment of leprosy. Acta Leprol., 1989, 7: 200-202.
  102. Choudhury A, Mistry NF, Antia NH. Effects of derivative of serotonin (deoxyfructoserotonin) and other antileprosy drugs on attachment and uptake of Mycobacterium leprae by Schwann cells In vitro.  Antimicrob. Agents Chemother., 1989, 33: 866-870.
  103. Birdi TJ, Antia NH. The macrophage in leprosy: A review on the current status. Int. J. Lepr., 1989, 57: 511-525.
  104. Marolia J, Mahadevan PR. Reactive oxygen intermediates inactivate Mycobacterium leprae in the phagocytes from human peripheral blood. Int. J. Lepr., 1989, 57: 483-491.
  105. Mistry NF, Antia NH. A critique on the interpretation of the lepromin reaction using heat-killed M. leprae vaccine. Int. J. Lepr., 1989, 57: 110-111.
  106. Desai S, Birdi TJ, Antia NH. Correlation between macrophage activation, bacterial function and antigen presentation of M. leprae in macrophages of leprosy patients and normal individuals. Infect. Immun., 1989, 57: 1311-1317.
  107. Mistry Y, Antia NH, Mukherjee R. Correlation of bacterial viability with uptake of 14C acetate into phenolic glycolipid-1 of Mycobacterium leprae within Schwannoma cells. J. Biosci., 1989, 14: 37-45.
  108. Mehta R, Birdi TJ, Antia NH. Effect of M. leprae infected Schwann cells and their supernatant on lymphocyte neuroglia interaction. J. Neuroimmunol., 1989, 22: 149-156.
  109. Shetty VP, Jacobs JM, Antia NH. The pathology of early leprous neuropathy. J. Neurol. Sci., 1988, 88: 115-131.
  110. Antia NH, Mistry NF, Kulkarni VC. Multiplication of armadillo derived M.leprae in murine dissociated Schwann cell cultures. Int. J. Lepr., 1988, 56: 632-635.
  111. Shetty VP, Antia NH. Nerve damage in Leprosy. Int. J. Lepr., 1988, 56: 619-620.
  112. Jagannathan R, Patil D, Mahadevan PR. Correlation of In vitro Fc receptor assay with In vivo mouse foot pad method. Indian J. Lepr., 1988, 60: 517-525.
  113. Ranade A, Mahadevan PR. A component of Mycobacterium leprae as a serodiagnostic tool for leprosy. Indian J. Biochem. Biophys., 1988, 25: 554-559.
  114. Marolia J, Mahadevan PR. Mycobacterium leprae mediated stimulation of macrophages from leprosy patients and hydrogen peroxide production. J. Biosci., 1988, 13: 295-303.
  115. Desai S, Birdi TJ, Antia NH. Presence of M.leprae specific lymphocytes in lymph nodes of lepromatous leprosy patients. Scand. J. Immunol., 1988, 28: 211-216.
  116. Mehta R, Mukherjee R, Landon D, Verghese G, Antia NH. In vitro interaction of M.leprae-infected Schwann cells and splenic cells. Acta Neuropathol., 1988, 76: 407-410.
  117. Antia NH, Birdi TJ. Leprosy vaccine - a reappraisal (Editorial).   Int. J. Lepr., 1988, 56: 310-313.
  118. Hooper M, Bhagaria A, Beveridge EG, Jagannathan R, Mahadevan PR, Yeap SK. The identification of novel tyrosinase inhibitors with In vitro activity against Mycobacterium leprae. Quaderni di cooperazione sanitaria - Health cooperation papers. 1988, 7: 259-270.
  119. Vermani M, Mahadevan PR. A component of Mycobacterium leprae as immunomodulating agent - Activation of macrophages to contain viability of M. leprae in vivo and in vitro. Quaderni di cooperazione sanitaria - Health cooperation papers. 1988, 7: 153-161.
  120. Antia NH, Uplekar MW, Ambrose EJ, Mahadevan PR, Mester L. Effect of Deoxyfructo Serotonin (DFS) on lepromatous Leprosy. Lancet, 1988, 1: 619-622.
  121. Robinson P, Mahadevan PR. A component of Mycobacterium leprae as immunomodulating agent for immune deficient cells of leprosy patients. J. Clin. Lab. Immunol., 1987, 24: 171-176.
  122. Jagannathan R, Mahadevan PR. Concurrence of the In vitro methods of Fc receptor assay and ATP estimation for viability of Mycobacterium leprae. Med. Sci. Res., 1987, 15: 1377-1378.
  123. Barros U, Ladliwala U, Birdi TJ, Antia NH. Localization and retention of mycobacterial antigen in lymph nodes of leprosy patients. Brit. J. Exp Pathol., 1987, 68: 733-741.
  124. Marolia J, Mahadevan PR. Superoxide production from macrophages of leprosy patients after stimulation with Mycobacterium leprae. J. Biosci., 1987, 12: 273-279.
  125. Barros U, Shetty VP, Antia NH. Demonstration of Mycobacterium leprae antigen in nerves of tuberculoid leprosy. Acta Neuropathol., 1987, 73: 387-392.
  126. Jacobs JM, Shetty VP, Antia NH. Teased fibre studies in leprous neuropathy. J. Neurol. Sci., 1987, 79: 301-313.
  127. Jacobs JM, Shetty VP, Antia NH. Myelin changes in leprous neuropathy. Acta Neuropathol., 1987, 74: 75-80.
  128. Bhagaria A, Mahadevan PR. A rapid method for viability and drug sensitivity of Mycobacterium leprae cultured in macrophages and using fluorescein diacetate. Indian J. Lepr., 1987, 59: 9-11.
  129. Vejare S, Mahadevan PR. Importance of determining viability of Mycobacterium leprae inside macrophages - an in vitro method using uracil. J. Biosci., 1987, 11: 455-463.
  130. Mahadevan PR, Jagannathan R, Bhagria A. In vitro drug test systems against M.leprae. Proceedings of the Indo-UK symposium on leprosy, Agra. 1986, 337-350.
  131. Birdi TJ, Antia NH. The macrophage defect in leprosy. Proceedings of the Indo-UK symposium on leprosy, Agra. 1986, 68-72.
  132. Mukherjee R, Antia NH. Host-parasite interrelationship between M.leprae and Schwann cells in vitro. Int. J. Lepr., 1986, 54: 632-638.
  133. Uplekar MW, Antia NH. Dapsone dependent nodular panniculitis. Indian J. Lepr., 1986, 58: 286-290.
  134. Mahadevan PR, Jagannathan R, Bhagria A, Vejare S, Agarwal S. Host - pathogen interaction - a new In vitro drug test systems against Mycobacterium leprae - their possibilities and limitations. Lepr. Rev., 1986, 57: 182-200.
  135. Uplekar MW, Antia NH. Clinical and histopathological observations on pure neuritic leprosy. Indian J. Lepr., 1986, 58: 513-521.
  136. Itty BM, Mukherjee R, Antia NH. Adherence of Mycobacterium leprae to Schwann Cells in vitro. J. Med. Microbiol., 1986, 22: 277-282.
  137. Talati S, Mahadevan PR. Lipase Activity in Mycobacterium leprae - and indicator of metabolic function. Indian J. Lepr., 1986, 58: 367-372.
  138. Shetty VP, George V. Xenograft studies in leprous neuropathy. Int. J. Lepr., 1986, 54: 133-135.
  139. Mistry NF, Birdi TJ, Antia NH. M. leprae phagocytosis and its association with membrane changes in macrophages from leprosy patients. Parasite Immunol., 1986, 8: 129-138.
  140. Agarwal S, Vemuri N, Mahadevan PR. Macrophage membrane alterations in leprosy as determined by change in sialic acid level. J. Clin. Lab. Immunol., 1986, 19: 119-122.
  141. Irani S, Mukherjee R, Jagannathan R, Antia NH. In vitro study of the effect of dapsone on the components of the peripheral nerve in organised nerve culture model. Indian J. Med. Res., 1986, 83: 449-452.
  142. Jagannathan R, Mahadevan PR. Minimum inhibitory concentration of drugs against Mycobacterium leprae as determined by an In vitro assay. J. Biosci., 1986, 10: 137-144.
  143. Birdi TJ, Salgame PR, Bharucha H, Antia NH. In vitro tests for screening of immunomodulating mycobacterial strains in leprosy. J. Biosci., 1986, 10: 127-135.
  144. Antia NH, Mistry NF. Plasma cells in caseous necrosis of nerves in leprosy. Lepr. Rev., 1985, 56: 331-335.
  145. Mukherjee R, Antia NH. Migration and proliferation of Schwann cells in adult human leprous nerve cultures. Lepr. Rev., 1985, 56: 321-330.
  146. Antia NH, Barros U, Shetty VP. Demonstration of M. leprae antigens in nerves of tuberculoid patients. Med. Sci., 1985, 13: 914-915.
  147. Mukherjee R, Antia NH. Adherence of M.leprae to Schwann cells in vitro: a specific phenomenon. IRCS Med. Sci., 1985, 13: 853-854.
  148. Mistry NF, Birdi TJ, Mahadevan PR, Antia NH. Mycobacterium leprae-induced alterations in macrophage Fc receptor expression and monocyte-lymphocyte interaction in familial contacts of leprosy patients. Scand. J. Immunol., 1985, 22: 415-423.
  149. Mahadevan PR. Host-parasite interaction in relation to leprosy Indian J. Lepr. 1985, 57: 239-257.
  150. Antia NH, Mukherjee R. Nerve tissue culture:  A useful model for the study of nerve damage in Hansen's disease. The Star, 1985, 45: 8-9.
  151. Vemuri N, Khandke L, Mahadevan PR, Hunter SW, Brennan PJ. Isolation of phenolic glycolipid I from human lepromatous nodules. Int. J. Lepr., 1985, 53: 487-489.
  152. Shetty VP, Mistry NF, Antia NH. Serum demyelinating factors and adjuvant like activity of Mycobacterium leprae:  Possible cause of early nerve damage in leprosy. Lepr. Rev., 1985, 56: 221-227.
  153. Ambrose EJ, Antia NH, Birdi TJ, Mahadevan PR, Mester L, Mistry NF, Mukherjee R, Shetty VP. The action of deoxyfructose serotonin on intracellular bacilli and on host response in leprosy. Lepr. Rev., 1985, 56: 199-208.
  154. Mukherjee R, Antia NH. Intracellular multiplication of leprosy-derived Mycobacteria in Schwann cells of dorsal root ganglion cultures. J. Clin. Microbiol., 1985, 21: 808-814.
  155. Talati S, Mahadevan PR. Lipase and penicillinase activity in Mycobacterium leprae. IRCS Med. Sci., 1985, 13: 290-291.
  156. Mukherjee R, Mistry Y, Antia NH, Klein N, Vemuri N. Incorporation of (14C)-acetate into the specific phenolic glycolipid of M.leprae maintained within cultured cells. IRCS Med. Sci., 1985, 13: 203-204.
  157. Jagannathan R, Mahadevan PR. Synergistic activity of dapsone and brodimoprim (a dihydrofolate inhibitor) against Mycobacterium leprae. IRCS Med. Sci., 1985, 13: 265-266.
  158. Shetty VP, Antia NH. Multiple axonal myelination in the experimental mouse leprosy model. Int. J. Lepr., 1984, 52: 249-251.
  159. Kamala AN, Antia NH, Shetty VP. Study of the involvement of the sciatic nerve following inoculation with M. leprae and other mycobacteria in the mouse foot pad. Int. J. Lepr., 1984, 52: 506-514.
  160. Marolia J, Mahadevan PR. Hydrolytic enzymes in macrophages from leprosy patients in presence of Mycobacterium leprae. Indian J. Lepr., 1984, 56: 776-783.
  161. Mankar MV, Jagannathan R, Mahadevan PR. In vitro drug screening system using membrane alteration in macrophages by Mycobacterium leprae. J. Biosci., 1984, 6: 709-716.
  162. Ramasesh N, Bhagaria A, Mahadevan PR. A rapid method for determining the viability of Mycobacterium leprae within macrophages. IRCS Med. Sci., 1984, 12: 1014-1015.
  163. Khandke L, Salgame PR, Mahadevan PR. In vitro lymphocyte stimulating ability of cell components of Mycobacterium leprae. IRCS Med. Sci., 1984, 12: 1012-1013.
  164. Birdi TJ, Mistry NF, Mahadevan PR, Antia NH. Antigen specific macrophage - lymphocyte interaction in lepromatous leprosy. J. Clin. Lab. Immunol., 1984, 13: 189-194.
  165. Salgame PR, Birdi TJ, Lad SJ, Mahadevan PR, Antia NH. Mechanism of immunosuppression in leprosy – macrophage membrane alterations. J. Clin. Lab. Immunol., 1984, 14: 145-149.
  166. Khandke L, Penumarti N, Mahadevan PR. Phosphatidylino-sitomannosides in lepromatous leprosy nodules. Indian J. Med. Res., 1984, 80: 259-263.
  167. Mistry NF, Birdi TJ, Antia NH. Suitability of kinetics of macrophage-lymphocyte interaction to distinguish between exposure and susceptibility to M. leprae. IRCS Med. Sci., 1984, 12: 839-840.
  168. Kamala AN, Shetty VP, Antia NH. Evaluation of the neurotoxicity of dapsone in the mouse model. Indian J. Lepr., 1984, 56: 251-256.
  169. Mehta LN, Antia NH. Ultrastructure of sciatic nerve of armadillo infected with Mycobacterium leprae. Indian J. Lepr., 1984, 56: 540-554.
  170. Antia NH, Birdi TJ. An overview on the leprosy vaccine. Indian J. Lepr., 1984, 56: 301-306.
  171. Salgame PR, Mahadevan PR, Antia NH. Production of antibody to suppressor factor(s) in macrophages of lepromatous leprosy patients. IRCS Med. Sci., 1984, 12: 736-737.
  172. Birdi TJ, Mistry NF, Mahadevan PR, Antia NH. In vitro studies on the effect of levamisole in lepromatous leprosy. J. Clin. Lab. Immunol., 1984, 13: 93-96.
  173. Nair I, Mahadevan PR. An In vitro test using cholesterol metabolism of macrophages to determine drug sensitivity and resistance of Mycobacterium leprae. J. Biosci., 1984, 6: 221-231.
  174. Birdi TJ, Salgame PR, Mahadevan PR, Antia NH. An indomethacin sensitive suppressor factor released by macrophages of leprosy patients. J. Biosci. 1984, 6: 125-134.
  175. Mistry NF, Birdi TJ, Uplekar M, Antia NH. A sequential histopathological study of the lepromin reaction in leprosy patients. IRCS Med. Sci., 1984, 12: 287-288.
  176. Birdi TJ, Antia NH. An In vitro method of screening for drug sensitivity. IRCS Med. Sci., 1984, 12: 256-257.
  177. Birdi TJ, Mistry NF, Mahadevan PR, Antia NH. Alterations in the membrane of macrophages from leprosy patients. Infect. Immun., 1983, 41: 121-127.
  178. Antia NH. Cultivation of M.leprae. Indian J. Lepr., 1983, 55: 420-423.
  179. Vithala L, Talati S, Mahadevan PR. An In vitro system to study drug sensitivity of Mycobacterium leprae using infected human tissue.  J. Biosci., 1983, 5: 235-241.
  180. Salgame PR, Mahadevan PR, Antia NH. Study of concanavalin A receptors on macrophages in leprosy. IRCS Med. Sci., 1983, 11: 991-992.
  181. Salgame PR, Mahadevan PR, Antia NH. Mechanism of immunosuppression in leprosy:  Presence of suppressor factor(s) from macrophages of lepromatous patients. Infect. Immun., 1983, 40: 1119-1126.
  182. Lad SJ, Salgame PR, Mahadevan PR. Surface membrane changes in lepromatous macrophages affecting the adherence of Mycobacterium leprae. J. Biosci., 1983, 5: 131-138.
  183. Donde SV, Shah A, Antia NH. Nerve conduction in leprosy: In vivo and in vitro study. Indian J. Lepr., 1983, 55: 12-21.
  184. Mistry NF, Birdi TJ, Mahadevan PR, Antia NH. Macrophage somatic hybrids in leprosy.  Technique standardization and dominance of lepromatous pattern of Fc receptor activity. IRCS Med. Sci., 1983, 11: 386-387.
  185. Antia NH, Kamala N. Persistence of M. leprae in the peripheral nerve. Indian J. Med. Res., 1983, 77: 420-422.
  186. Antia NH. Leprosy: A disease of the Schwann cell. Indian J. Lepr., 1982, 54: 599-604.
  187. Young DB. Mycobacterial lipids in infected tissue samples. Ann. Microbiol., 1982, 133: 53-58.
  188. Lad SJ, Mahadevan PR. Adherence of Mycobacterium leprae to macrophage as an indicator of pathogen induced membrane changes. Indian J. Med. Res., 1982, 76: 804-881.
  189. Kurup IG, Mahadevan PR. Cholesterol metabolism of macrophages in relation to presence M. leprae. J. Biosci., 1982, 4: 307-316.
  190. Khanolkar SR, Ambrose EJ, Mahadevan PR. Uptake of 3, 4-dihydroxy[3H] phenylalanine by Mycobacterium leprae isolated from frozen (-80oC) armadillo tissue. J. Gen. Microbiol., 1981, 127: 385-389.
  191. Shetty VP, Antia NH. Degeneration and regeneration of unmyelinated fibres in experimental leprous neuropathy. Int. J. Lepr., 1981, 49: 324-330.
  192. Vidyasagar PB, Damle PS, Antia NH. A study of the sciatic nerve compound action potential In vitro in normal and M. leprae infected mice. Indian J. Lepr., 1981, 53: 537-555.
  193. Young DB. Detection of mycobacterial lipids in skin biopsies from leprosy patients. Int. J. Lepr., 1981, 49: 198-204.
  194. Shetty KT, Antia NH, Krishnaswamy PR. Occurrence of - glutamyl transpeptidase activity in several mycobacteria including Mycobacterium leprae. Int. J. Lepr., 1981, 49: 49-56.
  195. Young, DB. Identification of M. leprae: Use of wall-bound mycolic acids. J. Gen. Microbiol., 1980, 121: 249-253.
  196. Jayaraman P, Mahadevan PR, Mester M, Mester L. Inhibition of the incorporation of (3H) DOPA M.leprae by desoxyfructo-serotonin. Biochem. Pharmacol., 1980, 29: 2526-2528.
  197. Mahadevan PR, Antia NH. Biochemical alteration in cells following phagocytosis of M.leprae - The consequence - A basic concept. Int. J. Lepr., 1980, 48: 167-171.
  198. Mukherjee R, Mahadevan PR, Antia NH. Organized nerve culture II - DNA synthesis in Schwann cells in the presence of M. leprae. Int. J. Lepr., 1980, 48: 189-192.
  199. Mukherjee R, Mahadevan PR, Antia NH. Organized nerve culture.  I - A technique to study the effect of M. leprae infection. Int. J. Lepr., 1980, 48: 183-188.
  200. Shetty VP, Antia NH. Myelination around multiple axons in the peripheral nerve: An unusual ultrastructural observation. Acta Neuropathol., 1980, 50: 147-151.
  201. Birdi TJ, Salgame PR, Mahadevan PR, Antia NH. Role of macrophages in defective cell mediated immunity in lepromatous leprosy. II - Macrophage and lymphocyte interaction. Int. J. Lepr., 1980, 48: 178-182.
  202. Salgame PR, Birdi TJ, Mahadevan PR, Antia NH. Role of macrophages in defective cell mediated immunity in lepromatous leprosy Factor(s) from macrophages affecting protein synthesis and lymphocyte transformation. Int. J. Lepr., 1980, 48: 172-177.
  203. Antia NH, Shetty VP, Mehta LN. Study of the evolution of nerve damage in leprosy. Part IV - An assessment. Indian J. Lepr., 1980, 52: 48-52.
  204. Shetty VP, Vidyasagar PB, Antia NH. Study of the evolution of nerve damage in leprosy. Part III - Sciatic nerve lesions in mice inoculated with M. leprae with nerve   conduction velocity correlates. Indian J. Lepr., 1980, 50: 26-47.
  205. Shetty VP, Mehta LN, Irani PF, Antia NH. Study of the evolution of nerve damage in leprosy: Part II - Observations on the index branch of the radial cutaneous nerve in contacts of leprosy. Indian J. Lepr., 1980, 52: 19-25.
  206. Shetty VP, Mehta LN, Irani PF, Antia NH. Study of the evolution of nerve damage in leprosy: Part I - Observations on the index branch of the radial cutaneous nerve in contacts of leprosy. Indian J. Lepr., 1980, 52: 19-25.
  207. Antia NH. Study of the evolution of nerve damage in leprosy: A general introduction. Indian J. Lepr., 1980, 52: 3-4.
  208. Birdi TJ, Salgame PR, Antia NH. The role of macrophages in leprosy as studied by protein synthesis of macrophages from resistant and susceptible hosts - A mouse and human study. Indian J. Lepr., 1979, 23-42.
  209. Khanolkar SR, Ambrose EJ, Chulawalla RG, Bapat CV. Auto radiographic  and  metabolic studies of  M. leprae.  Lepr. Rev., 1978, 49: 187-198.
  210. Ambrose EJ, Khanolkar SR, Chulawalla RG. A rapid test for bacillary resistance to dapsone. Indian J. Lepr., 1978, 50: 131-143.
  211. Antia NH. Radioisotope labeling of M. leprae.  Indian J. Lepr., 1978, 50: 123-125.
  212. Ambrose EJ, Khanolkar SR, Antia NH, Chulawalla RG, Koticha KK. Rapid test for drug resistance in leprosy. Lancet, 1977, 2: 1036.

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